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Melatonin

9 min read

The lack of melatonin leads to sleep disturbance, provoking insomnia, lowers the body’s adaptation to the changing time zones. The deficiencies of this hormone of the pineal gland may compensate by taking special drugs. Not only do they normalize sleep, but have a further positive impact. To get the maximum benefit, it is necessary to read rules of admission, indications for use, possible side effects.

The contents

  • 1. What is melatonin?
  • 2 Characteristic features of hormone
  • 3 Why and when to take the “sleep hormone”?
  • 4 the Effects and beneficial properties
    • 4.1 the Value in sports
    • 4.2 Effects on libido
    • 4.3 Influence on the concentration of testosterone
    • 4.4 Relationship to prolactin
    • 4.5 Impact on growth hormone
    • 4.6 Benefits for weight loss
  • 5 Indications and contraindications
  • 6 instructions for use
    • 6.1 Recommended dosage
    • 6.2 the duration of the course
  • 7 In what form is the drug available?
    • 7.1 Drugs with melatonin
    • 7.2 Sports nutrition
  • 8 Melatonin in food products
  • 9 Melatonin during pregnancy
  • 10 Interaction with other drugs
  • 11 Side effects, risks and harm
  • 12 conditions of sale and storage
  • 13 Analog of melatonin

What is melatonin?

Melatonin is called the hormone responsible for the regulation of the circadian rhythm of living organisms, that is, wakefulness and sleep. Compound helps to get rid of insomnia that occurs on a background of fatigue, irritability from the abrupt change time zone. Thanks to these features, it is often called the “sleep hormone”. Melatonin is a derivative of serotonin produced from the tryptophan.

The latter is an essential amino acid L-tryptophan. The highest concentration of hormone in the blood falls at night, namely, from midnight until five in the morning. The highest peak is reached in 2 hours of the night. Day the level of melatonin decreases. In other words, when a person is awake melatonin decreases and increases during sleep.

Characteristic features of hormone

The production of melatonin is directly due to the circadian rhythm. In the light, is the day of hormone is drastically reduced. In the dark on the contrary its concentration begins to rise. In the summer, when daylight rises, the synthesis of melatonin greatly decreases and in winter increases. Age also plays an important role.

The older the person becomes, the less melatonin is produced. It becomes a cause of deterioration of sleep. Man often tormented by insomnia, which adversely affects deep sleep. He becomes more irritable. Its systems and organs cease to properly recover. Melatonin leads to a decrease in systolic blood pressure.

Why and when to take the “sleep hormone”?

Melatonin need to accept people in the following situations:

  • The hormone is essential for those who suffer from insomnia, have difficulty falling asleep because of severe fatigue and prolonged wakefulness. If you increase the concentration of melatonin, the sleep problems greatly reduced. This substance has a sedative effect and has a calming effect on the nervous system.
  • Communication is required in every person that is experiencing increased irritability or due to the change in time zone or work schedule. Hormone helpful for those who engaged in physical activity, resulting in muscle fatigue. The substance helps to relax and to recover better during sleep.
  • The substance helps to cope with fatigue after workouts and fatigue.

    Effects and beneficial properties

    The main function of hormone is to improve the quality of sleep. The Union takes an active part in normalization of the endocrine system. Melatonin reduces emotional and physical activity, but only in the period when wakefulness becomes the obstacle to normal biorhythms.

    The hormone has positive side effects. It has antistress, antioxidant, immunostimulant, antitumor effects. In addition, it reduces the speed of the processes of aging. Along with the General properties, the compound exerts a specific influence, depending on the specific physical activities.

    The value in the sport

    Athletes take melatonin, primarily to improve sleep. This impact depends on the speed of regenerative processes of the body after sport. The higher the intensity, the more irritated nervous system. Such exposure has a negative impact on health.

    Sleep quality after heavy physical activity becomes much worse, and recovery requires much more time. If a person is experiencing insomnia, it means that the athlete will not be strong enough to perform specific tasks. Sleep allows the muscles to relax and the internal organs and nervous system to recover. What sleeps better athlete, the faster he recovers, and sports performance greatly improved.

    Effects on libido

    On this topic, there was a huge amount of research. They showed that no direct relationship between melatonin concentration and libido are there. Taking medications that increase the level of this substance, has no direct effect on the anabolic hormones, which are responsible for Amurskoe libido.

    Effect on concentration of testosterone

    The level of the male hormone has a positive effect on anabolic processes, sexual desire, sexual function. Melatonin has been shown in research that directly affects the production and does not suppress the synthesis of testosterone. Negative impact on male hormone has a female called prolactin. Such indirect influence is possible only under certain dosages.

    The relationship with prolactin

    Certain specific results concerning the relationship between melatonin and prolactin is not. Some studies have demonstrated the absence of any impact on the female hormone, but no further clarification regarding the duration and period of exposure were not specified.

    Young people who in the day took five milligrams per thirty days, it was revealed increased level of prolactin. The increase in the female hormone was recorded daily. The increase in the concentration of prolactin was observed not in the daytime, and at night, when melatonin levels reached the highest concentration.

    Effect on growth hormone

    Somatotropin (growth hormone) is dependent on melatonin. The “sleep hormone” has a positive effect on G, peak concentrations which occur in night time. Both compounds are produced by a rest period. Their concentration decreases with sleep problems and insomnia, which leads to decreased production and melatonin, and growth hormone.

    G a positive impact on the growth of cells not only in children but also in adults. It has catabolic and anabolic effects involved in the metabolism of carbohydrates, increases the absorption of calcium in bone tissue. Somatotropin is required not only in adolescence, but also those who are active in sports. The main feature of melatonin is that it has a positive effect on sleep quality and recovery. This hormone influences the production of growth hormone.

    Use for weight loss

    A lot of research on how melatonin affects a person’s weight. The hormone stimulates glucose uptake and accumulation in muscle tissues of glycogen. The substance stimulates increase in the production of creatine phosphate and energy, i.e. ATP. Similar effects can boost energy during exercise. It helps increase the duration of the training, which in turn contributes to greater burning fat. The effect of weight loss level of insulin and glucose helps reduce weight.

    Indications and contraindications

    Melatonin is recommended in disorders of sleep quality. If a person can’t sleep at night, he becomes irritable and begins to experience stress, which causes insomnia.

    Take the drug with melatonin it is impossible for those who suffer from diabetes, autoimmune diseases, myeloma, lymphoma, leukemia, epileptic seizures. The hormone is contraindicated for use for children up to twelve years. Adolescents with the drugs should be prescribed only by a specialist.

    Usage instructions

    Hormone intended for reception in the evening. It is best to use the drug thirty minutes before bedtime. The active ingredient starts to work after 45-60 minutes. When you take a hormone, you should avoid direct contact with bright light. It suppresses the effect after consuming the drug. Pills washed down with plenty of water.

    Recommended dosage

    Instruction and optimal daily dosage of the drug completely depends on how BAD the pharmacy or drug taking. You need to carefully examine how much melatonin is contained in one tablet. Daily optimal and safe levels of active substance amounts to up to three milligrams. In the early days is recommended to take one to two milligrams, then increase the dosage. The maximum dosage is 6 mg. Deterioration of health — signal that you must stop taking the Supplement.

    The duration of the course

    Melatonin is recommended to take within one month. More prolonged intake of the course (two months) is possible only on prescription. Next, be sure to take a break, equal to weeks. If the need arises, then after a week break repeat the course again. From three months to six months to take the drug may be prescribed for the elderly who are undergoing treatment to normalize blood pressure.

    In what form is the drug available?

    The Supplement is sold in the form of white tablets, which are then washed down with water. Some manufacturers produce the drug in the form of chewable pills.

    Medications with melatonin

    The hormone is contained in the following supplements:

  • Vita-melatoninin each pill which is enclosed to three milligrams of active substance. Produced in the United States. In one package a total of 30 tablets.
  • Malaramcontaining the same amount of melatonin that the American drug. Russian additives are produced in packs of 24 tablets.
  • Circadin, which is a Swiss drug. One pill contains two milligrams of the hormone.
  • Melaxen. Another additive. Each tablet is enclosed on three milligrams of the substance.
  • These drugs have proved as the most effective and time-tested.

    Sports nutrition

    People who are active in sports, it is recommended to not take pharmaceutical drugs and dietary Supplements. Manufacturers of sports nutrition develop and produce their own supplements that have a positive effect on the recovery processes after training in the phase of sleep. They have a positive anti-catabolic effect when the person experiences emotional, physical stress. Such effects have made these drugs popular with leading an active way of life.

    Biologically active supplements with melatonin are recommended to take at night (half an hour before bedtime). In addition, they are recommended for use when flying, if you change the time zone. Before the flight you should drink a Supplement per hour. Do not drink drug before training. The oppression of physical activity with disorientation leads to a decrease in efficiency from class. It is not recommended to drink the drug in the morning and throughout the day.

    The best manufacturers and sports supplements

    • Optimum Nutrition 100 tablets of 3 mg.
    • NOW Foods 60 capsules of 3 mg.
    • Ultimate Nutrition 60 pills 3 mg.
    • Scitec Nutrition 90 tablets of 1 mg.
    • Universal Nutrition with 60пилюлями 5 mg.

    If you compare pharmaceutical drugs and sports supplements with the active substance, the latter is much more profitable. The content of melatonin in each capsule is the same, but the number of tablets in dietary Supplements and more, but have lower cost.

    Melatonin in food products

    Most of the substance lies in the rice. The amount of the hormone which enters the body through food, is sufficiently small. It is not possible to obtain a sufficient dosage that would help to get positive effects in terms of improving sleep quality. Much greater are the benefits of eating foods with L-tryptophan, promotes the production of melatonin. To enhance the result, you want to make the Supplement hormone in the amount of 1 to 6 milligrams a day. Such dosages are to get out of the ordinary food is simply impossible.

    Melatonin during pregnancy

    Supplement take is contraindicated to women during pregnancy and lactation. Furthermore, it is not recommended to use the drug to women who plan to become pregnant, because the hormone possesses contraceptive property.

    Interaction with other drugs

    The drug with the means that block beta-adrenoretseptory, leads to a decrease in the production of the hormone. Supplementation with melatonin combines well with sleeping pills, providing a synergistic effect. The hormone increases the effectiveness of tamoxifen antitumor action. It enhances the antibacterial action of isoniazid.

    Side effects, risks and harm

    Melatonin is considered safe for intake. Some people may be individual intolerance expressed in loss of coordination, severe dryness, vomiting, nausea. In the morning some people may feel increased fatigue and poor health. Some pharmaceutical drugs cause irritability, increased heart rate and excitability, headache, dizziness, night sweats, loss of concentration, blurred vision, migraine.

    After receiving the “sleep hormone” is not recommended to sit behind the wheel of the vehicle. This is because melatonin has an effect on the decrease in attention and concentration. It is impossible to give the drug to children, as no studies on how it affects them is unknown. He can slow sexual development. Negatively the body affected and overdose if you take more than 30 milligrams when there is disorientation, loss of memory, reduced duration of sleep.

    Conditions of sale and storage

    Drugs released without the recipe even in pharmacies. Sports supplements presented available for sale. Tools must be stored in a purchased package, in a place where the temperature does not exceed 25 degree, protected from direct sunlight. Usually the shelf life of the drug is up to three years, but only with proper storage conditions.

    An analogue of melatonin

    Tryptophan is a dietary Supplement that in a daily dosage of 500 mg promotes the synthesis of serotonin. At night, the pleasure hormone is converted into melatonin. In addition, in this preparation contains vitamins B5, B6.

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